Substance is located on the second floor of the Neonopolis Complex in vibrant Downtown Las Vegas. This dystopian, futuristic entertainment destination promises unrivaled sensory experiences.
Substance Las Vegas Upcoming Events & Tickets
-
- Yellow Claw
- Friday, Oct. 10, 2025 at 10:00 pm
- Las Vegas, NV · Substance on Fremont · Ages: 21+
-
- Flosstradamus
- Friday, Oct. 24, 2025 at 10:00 pm
- Las Vegas, NV · Substance on Fremont · Ages: 21+