Substance on Fremont Event Calendar

Substance is located on the second floor of the Neonopolis Complex in vibrant Downtown Las Vegas. This dystopian, futuristic entertainment destination promises unrivaled sensory experiences.

Substance Las Vegas Upcoming Events & Tickets

Oct
31
• Wax Motif
• Friday, Oct. 31, 2025 at 10:00 pm
• Las Vegas, NV · Substance on Fremont · Ages: 21+
Nov
7
• Riot Ten
• Friday, Nov. 7, 2025 at 10:00 pm
• Las Vegas, NV · Substance on Fremont · Ages: 21+
Nov
21
• AC Slater
• Friday, Nov. 21, 2025 at 10:00 pm
• Las Vegas, NV · Substance on Fremont · Ages: 21+